Queensland COVID-19 research
This page of Queensland’s research related to the COVID-19 pandemic is compiled from information provided by Queensland universities and research institutes.
While many of our researchers are working on potential vaccines, treatments and other medical interventions, other researchers are applying their expertise to other impacts of the pandemic upon our economy and other aspects of society. The data includes immediate research activity, recent relevant work, proposed research (subject to available funds) and other responses using the resources and expertise of our research organisations.
Listing 1 matching response out of 149 total responses.
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The Impact of SARS-CoV-2 on the human blood-brain barrier August 2021
Neurological changes accompany at least 30% of COVID-19 cases (NeuroCOVID), however there remains little understanding of how this is related to viral infection, and its long-term consequences. The blood brain barrier (BBB) is a crucial link between the brain and the peripheral circulatory system, and evidence suggests SARS-CoV-2 infection, or the subsequent inflammatory response, can potentially lead to BBB impairment with consequences involving neuroinvasion of virus, and neuroinfiltration of immune factors. However, there is little understanding of viral interaction with human BBB cell-types. In this project, are using our established human BBB model to determine how SARS-CoV-2 impacts the BBB, whether anti-viral or anti-inflammatory drugs can protect the BBB, and are establishing a screening assay to measure impact of COVID-19 drugs on the BBB, and drug penetrance to the brain for treatment of neurological impairment in COVID-19.
#Neurological impairment
- Centre
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Cellular and Molecular Neurodegeneration Laboratory
QIMR Berghofer Medical Research Institute - Contact details
- A/Prof Anthony White
Principal Research Fellow
tony.white@qimrberghofer.edu.au
+614 1035 7010 - Collaborations
Other Queensland COVID-19 initiatives
- Queensland Government
- Coronavirus (COVID-19) business assistance finder
- Life Sciences Queensland
- Life Sciences Queensland joins the data-powered alliance to stop COVID-19
Key Australian COVID-19 initiatives
- Australian Academy of Science
- Rapid Research Information Forum (RRIF)
- COVID-19 Expert Database
Key international COVID-19 initiatives
- CORD-19 (COVID-19 Open Research Dataset)
- Free database of 130,000 plus COVID-19 open research papers